Major Opponents
- 86 Teams
| Record | Totals | Per Game | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff |
| 1 | Air Force | 1988 | 2003 | 6 | 2 | 4 | 0 | .333 | 126 | 200 | -74 | 21.0 | 33.3 | -12.3 |
| 2 | Akron | 2018 | 2018 | 1 | 0 | 1 | 0 | .000 | 34 | 39 | -5 | 34.0 | 39.0 | -5.0 |
| 3 | Arizona | 1975 | 1976 | 2 | 0 | 2 | 0 | .000 | 21 | 68 | -47 | 10.5 | 34.0 | -23.5 |
| 4 | Arizona State | 1977 | 2005 | 4 | 0 | 4 | 0 | .000 | 59 | 173 | -114 | 14.8 | 43.3 | -28.5 |
| 5 | Arkansas | 1981 | 1981 | 1 | 0 | 1 | 0 | .000 | 7 | 38 | -31 | 7.0 | 38.0 | -31.0 |
| 6 | Army | 1951 | 2011 | 5 | 3 | 2 | 0 | .600 | 99 | 96 | 3 | 19.8 | 19.2 | 0.6 |
| 7 | Auburn | 2009 | 2020 | 2 | 1 | 1 | 0 | .500 | 70 | 57 | 13 | 35.0 | 28.5 | 6.5 |
| 8 | Ball State | 2015 | 2015 | 1 | 1 | 0 | 0 | 1.000 | 24 | 19 | 5 | 24.0 | 19.0 | 5.0 |
| 9 | Beloit | 1894 | 1905 | 8 | 4 | 2 | 2 | .625 | 102 | 83 | 19 | 12.8 | 10.4 | 2.4 |
| 10 | Boston College | 1961 | 2012 | 5 | 4 | 1 | 0 | .800 | 113 | 100 | 13 | 22.6 | 20.0 | 2.6 |
| 11 | Bowling Green | 2001 | 2017 | 3 | 1 | 2 | 0 | .333 | 115 | 78 | 37 | 38.3 | 26.0 | 12.3 |
| 12 | California | 1948 | 2014 | 3 | 2 | 1 | 0 | .667 | 88 | 75 | 13 | 29.3 | 25.0 | 4.3 |
| 13 | Carlisle | 1903 | 1903 | 1 | 0 | 1 | 0 | .000 | 0 | 28 | -28 | 0.0 | 28.0 | -28.0 |
| 14 | Central Michigan | 2010 | 2025 | 2 | 2 | 0 | 0 | 1.000 | 64 | 32 | 32 | 32.0 | 16.0 | 16.0 |
| 15 | Chicago | 1892 | 1926 | 37 | 8 | 26 | 3 | .257 | 207 | 618 | -411 | 5.6 | 16.7 | -11.1 |
| 16 | Colgate | 1949 | 1949 | 1 | 1 | 0 | 0 | 1.000 | 39 | 20 | 19 | 39.0 | 20.0 | 19.0 |
| 17 | Colorado | 1951 | 1978 | 2 | 1 | 1 | 0 | .500 | 42 | 69 | -27 | 21.0 | 34.5 | -13.5 |
| 18 | Dartmouth | 1928 | 1928 | 1 | 1 | 0 | 0 | 1.000 | 27 | 6 | 21 | 27.0 | 6.0 | 21.0 |
| 19 | Drake | 1916 | 1938 | 2 | 2 | 0 | 0 | 1.000 | 73 | 6 | 67 | 36.5 | 3.0 | 33.5 |
| 20 | Duke | 1985 | 2024 | 24 | 10 | 14 | 0 | .417 | 523 | 569 | -46 | 21.8 | 23.7 | -1.9 |
| Record | Totals | Per Game | ||||||||||||
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff |
| 21 | Eastern Michigan | 2006 | 2009 | 3 | 3 | 0 | 0 | 1.000 | 67 | 44 | 23 | 22.3 | 14.7 | 7.7 |
| 22 | Florida | 1965 | 1966 | 2 | 0 | 2 | 0 | .000 | 21 | 67 | -46 | 10.5 | 33.5 | -23.0 |
| 23 | Great Lakes Navy | 1918 | 1944 | 4 | 1 | 2 | 1 | .375 | 13 | 73 | -60 | 3.3 | 18.3 | -15.0 |
| 24 | Hawaii | 1998 | 2004 | 2 | 1 | 1 | 0 | .500 | 88 | 70 | 18 | 44.0 | 35.0 | 9.0 |
| 25 | Illinois | 1892 | 2025 | 119 | 55 | 59 | 5 | .483 | 2023 | 2393 | -370 | 17.0 | 20.1 | -3.1 |
| 26 | Indiana | 1899 | 2024 | 84 | 47 | 36 | 1 | .565 | 1456 | 1554 | -98 | 17.3 | 18.5 | -1.2 |
| 27 | Iowa | 1900 | 2024 | 85 | 28 | 54 | 3 | .347 | 1233 | 2142 | -909 | 14.5 | 25.2 | -10.7 |
| 28 | Iowa Pre-Flight | 1942 | 1942 | 1 | 0 | 1 | 0 | .000 | 12 | 20 | -8 | 12.0 | 20.0 | -8.0 |
| 29 | Iowa State | 1895 | 1956 | 8 | 7 | 1 | 0 | .875 | 191 | 91 | 100 | 23.9 | 11.4 | 12.5 |
| 30 | Kansas | 2003 | 2004 | 2 | 2 | 0 | 0 | 1.000 | 48 | 37 | 11 | 24.0 | 18.5 | 5.5 |
| 31 | Kansas State | 1938 | 1941 | 2 | 2 | 0 | 0 | 1.000 | 72 | 3 | 69 | 36.0 | 1.5 | 34.5 |
| 32 | Kentucky | 1928 | 2017 | 2 | 2 | 0 | 0 | 1.000 | 31 | 23 | 8 | 15.5 | 11.5 | 4.0 |
| 33 | Knox | 1900 | 1902 | 2 | 1 | 1 | 0 | .500 | 11 | 20 | -9 | 5.5 | 10.0 | -4.5 |
| 34 | Lake Forest | 1893 | 1899 | 6 | 4 | 1 | 1 | .750 | 108 | 66 | 42 | 18.0 | 11.0 | 7.0 |
| 35 | Lombard | 1903 | 1903 | 1 | 1 | 0 | 0 | 1.000 | 23 | 0 | 23 | 23.0 | 0.0 | 23.0 |
| 36 | Louisiana-Monroe | 2025 | 2025 | 1 | 1 | 0 | 0 | 1.000 | 42 | 7 | 35 | 42.0 | 7.0 | 35.0 |
| 37 | Marquette | 1934 | 1934 | 1 | 1 | 0 | 0 | 1.000 | 21 | 12 | 9 | 21.0 | 12.0 | 9.0 |
| 38 | Maryland | 2017 | 2024 | 5 | 4 | 1 | 0 | .800 | 174 | 92 | 82 | 34.8 | 18.4 | 16.4 |
| 39 | Massachusetts | 2019 | 2019 | 1 | 1 | 0 | 0 | 1.000 | 45 | 6 | 39 | 45.0 | 6.0 | 39.0 |
| 40 | Miami (FL) | 1961 | 1968 | 4 | 2 | 2 | 0 | .500 | 54 | 52 | 2 | 13.5 | 13.0 | 0.5 |
| Record | Totals | Per Game | ||||||||||||
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff |
| 41 | Miami (OH) | 1963 | 2024 | 10 | 4 | 6 | 0 | .400 | 186 | 195 | -9 | 18.6 | 19.5 | -0.9 |
| 42 | Michigan | 1892 | 2025 | 78 | 15 | 61 | 2 | .205 | 874 | 2108 | -1234 | 11.2 | 27.0 | -15.8 |
| 43 | Michigan State | 1959 | 2021 | 57 | 16 | 41 | 0 | .281 | 1014 | 1741 | -727 | 17.8 | 30.5 | -12.8 |
| 44 | Minnesota | 1892 | 2025 | 99 | 38 | 56 | 5 | .409 | 1744 | 2194 | -450 | 17.6 | 22.2 | -4.5 |
| 45 | Mississippi State | 2012 | 2012 | 1 | 1 | 0 | 0 | 1.000 | 34 | 20 | 14 | 34.0 | 20.0 | 14.0 |
| 46 | Missouri | 1915 | 2008 | 8 | 4 | 4 | 0 | .500 | 152 | 146 | 6 | 19.0 | 18.3 | 0.8 |
| 47 | Navy | 1950 | 2002 | 3 | 3 | 0 | 0 | 1.000 | 87 | 47 | 40 | 29.0 | 15.7 | 13.3 |
| 48 | Nebraska | 1902 | 2025 | 18 | 7 | 11 | 0 | .389 | 347 | 515 | -168 | 19.3 | 28.6 | -9.3 |
| 49 | Nevada | 2006 | 2017 | 3 | 2 | 1 | 0 | .667 | 88 | 82 | 6 | 29.3 | 27.3 | 2.0 |
| 50 | Nevada-Las Vegas | 1998 | 2019 | 3 | 3 | 0 | 0 | 1.000 | 108 | 49 | 59 | 36.0 | 16.3 | 19.7 |
| 51 | North Carolina | 1976 | 1977 | 2 | 0 | 2 | 0 | .000 | 7 | 53 | -46 | 3.5 | 26.5 | -23.0 |
| 52 | Northern Illinois | 1975 | 2014 | 8 | 6 | 1 | 1 | .813 | 207 | 125 | 82 | 25.9 | 15.6 | 10.3 |
| 53 | Notre Dame | 1899 | 2018 | 47 | 9 | 37 | 1 | .202 | 411 | 1072 | -661 | 8.7 | 22.8 | -14.1 |
| 54 | Ohio | 1973 | 2021 | 5 | 4 | 1 | 0 | .800 | 129 | 49 | 80 | 25.8 | 9.8 | 16.0 |
| 55 | Ohio State | 1913 | 2024 | 81 | 14 | 66 | 1 | .179 | 789 | 2292 | -1503 | 9.7 | 28.3 | -18.6 |
| 56 | Oklahoma | 1939 | 1997 | 4 | 3 | 1 | 0 | .750 | 88 | 39 | 49 | 22.0 | 9.8 | 12.3 |
| 57 | Oregon | 1974 | 2025 | 2 | 1 | 1 | 0 | .500 | 28 | 44 | -16 | 14.0 | 22.0 | -8.0 |
| 58 | Oregon State | 1957 | 1966 | 4 | 3 | 1 | 0 | .750 | 49 | 38 | 11 | 12.3 | 9.5 | 2.8 |
| 59 | Penn State | 1993 | 2025 | 22 | 6 | 16 | 0 | .273 | 394 | 650 | -256 | 17.9 | 29.5 | -11.6 |
| 60 | Pittsburgh | 1949 | 2016 | 7 | 4 | 3 | 0 | .571 | 141 | 141 | 0 | 20.1 | 20.1 | 0.0 |
| Record | Totals | Per Game | ||||||||||||
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff |
| 61 | Purdue | 1895 | 2025 | 90 | 36 | 53 | 1 | .406 | 1482 | 1879 | -397 | 16.5 | 20.9 | -4.4 |
| 62 | Rice | 1967 | 2011 | 7 | 3 | 4 | 0 | .429 | 142 | 190 | -48 | 20.3 | 27.1 | -6.9 |
| 63 | Rutgers | 1919 | 2023 | 6 | 2 | 4 | 0 | .333 | 91 | 134 | -43 | 15.2 | 22.3 | -7.2 |
| 64 | South Carolina | 1962 | 1962 | 1 | 1 | 0 | 0 | 1.000 | 37 | 20 | 17 | 37.0 | 20.0 | 17.0 |
| 65 | Southern California | 1952 | 2025 | 6 | 0 | 6 | 0 | .000 | 69 | 194 | -125 | 11.5 | 32.3 | -20.8 |
| 66 | Southern Methodist | 1970 | 1970 | 1 | 0 | 1 | 0 | .000 | 20 | 21 | -1 | 20.0 | 21.0 | -1.0 |
| 67 | Stanford | 1933 | 2019 | 8 | 2 | 4 | 2 | .375 | 122 | 145 | -23 | 15.3 | 18.1 | -2.9 |
| 68 | Syracuse | 1940 | 2013 | 11 | 6 | 5 | 0 | .545 | 308 | 265 | 43 | 28.0 | 24.1 | 3.9 |
| 69 | TCU | 1999 | 2004 | 4 | 1 | 3 | 0 | .250 | 100 | 144 | -44 | 25.0 | 36.0 | -11.0 |
| 70 | Tennessee | 1996 | 2015 | 2 | 0 | 2 | 0 | .000 | 34 | 93 | -59 | 17.0 | 46.5 | -29.5 |
| 71 | Texas | 1942 | 1942 | 1 | 1 | 0 | 0 | 1.000 | 3 | 0 | 3 | 3.0 | 0.0 | 3.0 |
| 72 | Texas A&M | 2011 | 2011 | 1 | 0 | 1 | 0 | .000 | 22 | 33 | -11 | 22.0 | 33.0 | -11.0 |
| 73 | Texas Tech | 2010 | 2010 | 1 | 0 | 1 | 0 | .000 | 38 | 45 | -7 | 38.0 | 45.0 | -7.0 |
| 74 | Tulane | 1925 | 2025 | 5 | 1 | 4 | 0 | .200 | 37 | 82 | -45 | 7.4 | 16.4 | -9.0 |
| 75 | UCLA | 1931 | 2025 | 7 | 4 | 3 | 0 | .571 | 127 | 138 | -11 | 18.1 | 19.7 | -1.6 |
| 76 | Utah | 1927 | 2023 | 4 | 3 | 1 | 0 | .750 | 58 | 75 | -17 | 14.5 | 18.8 | -4.3 |
| 77 | UTEP | 2023 | 2023 | 1 | 1 | 0 | 0 | 1.000 | 38 | 7 | 31 | 38.0 | 7.0 | 31.0 |
| 78 | Vanderbilt | 1947 | 2012 | 4 | 2 | 1 | 1 | .625 | 66 | 57 | 9 | 16.5 | 14.3 | 2.3 |
| 79 | Wabash | 1905 | 1905 | 1 | 1 | 0 | 0 | 1.000 | 5 | 0 | 5 | 5.0 | 0.0 | 5.0 |
| 80 | Wake Forest | 1991 | 1997 | 4 | 2 | 2 | 0 | .500 | 114 | 83 | 31 | 28.5 | 20.8 | 7.8 |
| Record | Totals | Per Game | ||||||||||||
| Rk | Opponent | From | To | G | W | L | T | Pct | PS | PA | Diff | PS | PA | Diff |
| 81 | Washington | 1980 | 2024 | 4 | 0 | 4 | 0 | .000 | 12 | 129 | -117 | 3.0 | 32.3 | -29.3 |
| 82 | Washington (MO) | 1903 | 1903 | 1 | 1 | 0 | 0 | 1.000 | 23 | 0 | 23 | 23.0 | 0.0 | 23.0 |
| 83 | Washington State | 1958 | 1958 | 1 | 1 | 0 | 0 | 1.000 | 29 | 28 | 1 | 29.0 | 28.0 | 1.0 |
| 84 | Western Michigan | 2013 | 2016 | 2 | 1 | 1 | 0 | .500 | 59 | 39 | 20 | 29.5 | 19.5 | 10.0 |
| 85 | Wisconsin | 1892 | 2024 | 103 | 37 | 62 | 4 | .379 | 1619 | 2460 | -841 | 15.7 | 23.9 | -8.2 |
| 86 | Wyoming | 1979 | 1979 | 1 | 1 | 0 | 0 | 1.000 | 27 | 22 | 5 | 27.0 | 22.0 | 5.0 |


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